Light effects on the activity of several genes have recently been exploited in studies of plant gene expression. We discuss here some examples involving nuclear genes of higher plants, with emphasis on responses mediated by the phytochrome system. Recent work has revealed considerable diversity in the responses of different genes, indicating that several different regulatory programs are probably involved. A start has been made in studies of nuclear events associated with the changes in expression. Transcriptional regulation almost certainly occurs, although (...) many details remain to be studied and effects on mRNA processing and turnover have not been ruled out. Recent in vitro mutagenesis and gene transfer experiments with the gene for the small subunit of RuBP carboxylase indicate that sequences involved in regulating the level of expression in the light are located 5′ to the gene within about 1 kb of the start of transcription. (shrink)

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work.This work is in the public domain in (...) the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work.As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant. (shrink)

The volume documents, and makes an original contribution to, an astonishing period in twentieth-century philosophy—the progress of Arne Naess's ecophilosophy from its inception to the present. It includes Naess's most crucial polemics with leading thinkers, drawn from sources as diverse as scholarly articles, correspondence, TV interviews and unpublished exchanges. The book testifies to the skeptical and self-correcting aspects of Naess's vision, which has deepened and broadened to include third world and feminist perspectives. Philosophical Dialogues is an essential addition to the (...) literature on environmental philosophy. (shrink)

Biological evolution provides a creative fount of complex and subtle adaptations, often surprising the scientists who discover them. However, because evolution is an algorithmic process that transcends the substrate in which it occurs, evolution’s creativity is not limited to nature. Indeed, many researchers in the field of digital evolution have observed their evolving algorithms and organisms subverting their intentions, exposing unrecognized bugs in their code, producing unexpected adaptations, or exhibiting outcomes uncannily convergent with ones in nature. Such stories routinely reveal (...) creativity by evolution in these digital worlds, but they rarely fit into the standard scientific narrative. Instead they are often treated as mere obstacles to be overcome, rather than results that warrant study in their own right. The stories themselves are traded among researchers through oral tradition, but that mode of information transmission is inefficient and prone to error and outright loss. Moreover, the fact that these stories tend to be shared only among practitioners means that many natural scientists do not realize how interesting and lifelike digital organisms are and how natural their evolution can be. To our knowledge, no collection of such anecdotes has been published before. This paper is the crowd-sourced product of researchers in the fields of artificial life and evolutionary computation who have provided first-hand accounts of such cases. It thus serves as a written, fact-checked collection of scientifically important and even entertaining stories. In doing so we also present here substantial evidence that the existence and importance of evolutionary surprises extends beyond the natural world, and may indeed be a universal property of all complex evolving systems. (shrink)

This book is a collection of secondary essays on America's most important philosophic thinkers—statesmen, judges, writers, educators, and activists—from the colonial period to the present. Each essay is a comprehensive introduction to the thought of a noted American on the fundamental meaning of the American regime.

It is now well-known that Newton–Cartan theory is the correct geometrical setting for modelling the quantum Hall effect. In addition, in recent years edge modes for the Newton–Cartan quantum Hall effect have been derived. However, the existence of these edge modes has, as of yet, been derived using only orthodox methodologies involving the breaking of gauge-invariance; it would be preferable to derive the existence of such edge modes in a gauge-invariant manner. In this article, we employ recent work by Donnelly (...) and Freidel in order to accomplish exactly this task. Our results agree with known physics, but afford greater conceptual insight into the existence of these edge modes: in particular, they connect them to subtle aspects of Newton–Cartan geometry and pave the way for further applications of Newton–Cartan theory in condensed matter physics. (shrink)

The Doctrine of Double Effect (DDE) is an influential non-consequentialist principle positing a role for intention in affecting the moral permissibility of some actions. In particular, the DDE focuses on the intend/foresee distinction, the core claim being that it is sometimes permissible to bring about as a foreseen but unintended side-effect of one’s action some harm it would have been impermissible to aim at as a means or as an end, all else being equal. This article explores the meaning and (...) application of the DDE along with current debates over the nature of the intend/foresee distinction and its moral significance. How is the line between intended effects and merely foreseen but unintended side-effects to be drawn, and how are problem cases best handled? What is an appropriate methodology for debating the tenability of the DDE? How might the DDE interact with other non-consequentialist principles, and how might it be modified to capture other related factors (resulting perhaps in a Doctrine of Triple Effect) or to avoid certain problem cases? Does the DDE make permissibility turn on the actual intentions of particular agents, as critics such as Thomson and Scanlon assume, or is the role of intention more abstract? (shrink)

In [4], Kunen used iterated ultrapowers to show that ifUis a normalκ-complete nontrivial ultrafilter on a cardinalκthenL[U], the class of sets constructive fromU, has only the ultrafilterU∩L[U] and this ultrafilter depends only onκ. In this paper we extend Kunen's methods to arbitrary sequencesUof ultrafilters and obtain generalizations of these results. In particular we answer Problem 1 of Kunen and Paris [5] which asks whether the number of ultrafilters onκcan be intermediate between 1 and 22κ. If there is a normalκ-complete ultrafilterUonκsuch (...) that {α <κ: α is measurable} ∈Uthen there is an inner model with exactly two normal ultrafilters onκ, and ifκis super-compact then there are inner models havingκ+ +,κ+or any cardinal less than or equal toκnormal ultrafilters.These methods also show that several properties ofLwhich had been shown to hold forL[U] also hold forL[U]: using an idea of Silver we show that inL[U] the generalized continuum hypothesis is true, there is a Souslin tree, and there is awell-ordering of the reals. In addition we generalize a result of Kunen to characterize the countaby complete ultrafilters ofL[U]. (shrink)

This functional Magnetic Resonance Imaging study investigated high and low suggestible people responding to two visual hallucination suggestions with and without a hypnotic induction. Participants in the study were asked to see color while looking at a grey image, and to see shades of grey while looking at a color image. High suggestible participants reported successful alterations in color perception in both tasks, both in and out of hypnosis, and showed a small benefit if hypnosis was induced. Low suggestible people (...) could not perform the tasks successfully with or without the hypnotic induction. The fMRI results supported the self report data, and changes in brain activity were found in a number of visual areas. The results indicate that a hypnotic induction, although having the potential to enhance the ability of high suggestible people, is not necessary for the effective alteration of color perception by suggestion. (shrink)

Ford’s Helen Keller Was Never in a Chinese Room claims that my argument in How Helen Keller Used Syntactic Semantics to Escape from a Chinese Room fails because Searle and I use the terms ‘syntax’ and ‘semantics’ differently, hence are at cross purposes. Ford has misunderstood me; this reply clarifies my theory.

INTRODUCTION Adam Wodeham, OFM (d.) has received only passing mention in the textbooks on the history of medieval philosophy. Although recognized as a major ...

In his essay “Afterwords”, Kuhn describes his “double goal” as To justify that science achieves knowledge of nature, and at the same time, To show that science neither achieves, nor should aim towards achieving, truth. I hold that Kuhn’s denial of truth helps to bring out a tension between the two goals of his enterprise: Kuhn cannot both maintain that science achieves knowledge of nature and dismiss the notion of truth altogether from his philosophy of science. The same arguments that (...) attack truth will ultimately damage the quest for knowledge. In this chapter, I intend explore this problem—which I will call the problem of inconsistency—and ultimately provide a defense on behalf of Kuhn. I argue that Kuhn can achieve both of his goals, and so remain consistent, by reevaluating the notion of truth in his philosophy of science. Here, I introduce an alternative correspondence theory of truth, which I call the phenomenal-world correspondence theory of truth. I will argue that Kuhn’s philosophy of science will remain consistent with this alternative view of correspondence. I believe that this notion of truth not only succeeds in defending Kuhn’s enterprise from the problem of inconsistency, but is also a kind of truth that Kuhn can accept into his philosophical enterprise despite his rejection of the traditional correspondence theory. (shrink)

Against the background of changing assessments of Nominalism and its meanings before Ockham, this book examines the reception of Ockham's thought at Oxford and ...

Throughout the developing world, it is a well-documented fact that women farmers tend to get lower yields than their male counterparts. Typically this is attributed to disproportionate access to high-quality inputs and labor, with some even arguing there could be a skills-gap stemming from unbalanced access to training and education. This article examines the gender-based yield gap in the context of Zambian maize producers. In addition to the usual drivers, we argue that Zambia’s patriarchal and multi-tiered land distribution system could (...) disfavor women with respect to accessing quality soils. We are uniquely able to control for soil characteristics using farm data from a sample of 1573 fields with accompanying soil analysis. We find an expected difference in yields, but no evidence of a gap in unobserved characteristics, like skill, after controlling for access to inputs, especially quality soil, suggesting women are indeed disproportionately disadvantaged. We discuss how our findings could be used to develop self-targeting policy interventions that could empower women and would be consistent with the government’s stated equity goals. (shrink)

This article argues that theism entails a species of pantheism on the grounds that there is simply no discernible difference between the God's knowledge of the world and the world that God knows. The case against this thesis begins with the traditional theory of distinctions. But since God is necessarily omniscient there is not even the possibility that these might be considered apart and thus distinguished in that way. But neither is it possible to do this by means of Leibnitz's (...) law, that is, by finding some feature possessed by the one but not the other. Three potential areas of difference are considered but rejected, first, that knowledge unlike the world is representational, and second, that knowledge unlike the world is phenomenal – there is something that it is like to have. Both of these features, though able to distinguish ordinary knowledge from its objects, cease to provide the difference we require when extended to the case of divine knowledge. A final area of potential difference lies in the transcendent nature of God over the world, especially with respect to time, finitude and possibility. But this, in the end, is found no more able to distinguish God's knowledge from its object than the previous two suggestions. (shrink)

This essay presents and defends a triage theory of grading: An item to be graded should get full credit if and only if it is clearly or substantially correct, minimal credit if and only if it is clearly or substantially incorrect, and partial credit if and only if it is neither of the above; no other (intermediate) grades should be given. Details on how to implement this are provided, and further issues in the philosophy of grading (reasons for and against (...) grading, grading on a curve, and the subjectivity of grading) are discussed. (shrink)

This four volume set is a collection of some of the most significant scholarship published on the philosophy of Socrates in the last half century. The contributors include many of the most prominent scholars in this field. As the growth in Socratic studies in the past three decades is due in large part to the influential work of Gregory Vlastos, articles by him figure prominently in the collection, and works by other authors are generally related to his work. The volumes (...) deal with different areas of Socratic thought. The first volume begins with the question whether and to what degree we can discern a distinctive philosophy of Socrates in the ancient sources. The second volume deals with the trial of Socrates and the philosophical issues that arise from it. The third volume considers the philosophical methodology of Socrates and the fourth his moral philosophy. This collection shares some material with earlier collections on the philosophy of Socrates, but it is more extensive and up-to-date. Unlike other collections, which may offer the reader only a single article on a given topic, this collection offers a conversation in-depth. The reader can thus get a sense of the dimensions of the scholarly debate on these central issues in the philosophy of Socrates. No collection can be complete, but this aims at a representative portrait of Socratic studies in the last fifty years. (shrink)

While epistemic democrats have claimed that majority rule recruits the wisdom of the crowd to identify correct answers to political problems, the conjecture remains abstract. This article illustrates how majority rule leverages the epistemic capacity of the electorate to practically enhance the instrumental value of elections. To do so, we identify a set of sufficient conditions that effect such a majority rule mechanism, even when the decision in question is multidimensional. We then look to the case of sociotropic economic voting (...) in US presidential elections to provide empirical tractability for these conditions. We find that absent such an epistemic capacity a number of presidential elections might well have been decided differently. By generating clear conditions for the plausibility of claims made by epistemic democrats, and demonstrating their correspondence to empirical data, this article strengthens the broader instrumental grounds recommending democracy. (shrink)

This paper seeks to explore the significance of a specific kind of religious experience for the rationality of religious belief. The context for this is a gap between what is often allowed as rational and what is embraced as certain in the life of faith. The claim to certainty at issue is related to the work and experience of the Holy Spirit; this experience has a structure which is explored phenomenologically. Thereafter various ways of cashing in the epistemic value of (...) the purported claim to certainty are examined. (shrink)

In this article I argue (against the views of Russell Dancy and Gregory Vlastos, but in support of the views of R. E. Allen, Gail Fine, and Francesco Fronterotta) that Euthyphro 5c-d and 6d-e show that Socrates had a metaphysics, early version of the theory of forms. I disagree with Fronterotta only on the separation of the forms in the Euthyphro.

We believe that clinical ethics consultants (CECs) should offer advice, options, and recommendations to attending physicians and their teams. In their article in this issue of The Journal of Clinical Ethics, however, Kornfeld and Prager give CECs a somewhat different role. The CEC they describe may at times be more aptly understood as a medical interventionist who appropriates the roles of the attending physician and the medical team than as a traditional CEC. In these remarks, we distinguish the role of (...) the CEC from that of the physician, in contrast to some of these authors’ recommendations, which confuse the two roles. (shrink)

The moral nature of humanity has been debated and discussed by philosophers, theologians, and others for centuries. Only recently have neuroscientists and neuropsychologists joined the conversation by publishing a number of studies using newer brain scanning techniques directed at regions of the brain related to social behavior. Is it possible to relate particular brain structures and functions to the behavior of people, deemed evil, who violate all the tenets of proper behavior laid down by ancient and holy texts, prohibiting lying, (...) cheating, stealing, and murder? Is it possible that the recently discovered “mirror neurons” in the brain are the basis for empathy and that deficits in these brain cells lead to severe difficulty in relating socially to other people, including parents and siblings? What do we make of reports that the fusiform face area in the temporal lobe of the brain is specialized for the perception of faces and that defects in this region are seen regularly in individuals who are psychopathic. (shrink)

All too often, studies of death are reduced to a series of legal or medical case studies, which ignore the need to provide a personal and a societal context. This title explores the practical and philosophical questions related to death and dying. It looks at death from the perspective of different cultures and different periods in history.